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M13 Bacteriophage

01Nano-bio Material

Exhibiting a high surface area, enhanced reactivity, and the ability to be engineered for specific properties, nanobiomaterials are widely utilized across various industries. Eric Drexler, a pioneer of nanotechnology, identified three key characteristics for future materials: Self-evolving, Self-replicating, Self-assembling. Nanobiomaterials are advanced functional materials capable of meeting these three conditions.

02Virus

Poised at the boundary of living and non-living matter, viruses consist of an internal nucleic acid and an external protein shell implemented by the nucleic acid. Their remarkable uniformity in size offers a key advantage in material fabrication. Furthermore, since most viruses infect only specific hosts, they serve as an ideal material for high-precision targeting. Bacteriophage, a type of virus, is a compound word derived from 'bacteria' and 'phage'. As its name implies, it is a virus that only infects specific E. coli bacteria.

Zika virus
Ebola virus
Tobacco Mosaic Virus
λ Bacteriophage
T4 Bacteriophage

03M13 Bacteriophage

Distinguished from other bacteriophages, the M13 bacteriophage possesses a high aspect ratio (exceeding 1:130) and is enveloped by 2700 peptide pairs on its surface. This unique structure makes it an optimal platform for the expression of diverse functional groups. Beyond these characteristics, it is harmless to the human body and exhibits properties conducive to device fabrication. This positions it as an advanced next-generation material utilized in various industries, including high-performance energy devices and semiconductor applications.

T4 phage
VS

Defective (Harmful) Superior (Safe)

Harmfulness
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Design (Property)
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Structuring (Shape)
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Productivity (Quantity)
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Tobacco Mosic virus
VS

Defective (Harmful) Superior (Safe)

Harmfulness
01 02 03 04 05
Design (Property)
01 02 03 04 05
Structuring (Shape)
01 02 03 04 05
Productivity (Quantity)
01 02 03 04 05
M13 phage

Defective (Harmful) Superior (Safe)

Harmfulness
01 02 03 04 05
Design (Property)
01 02 03 04 05
Structuring (Shape)
01 02 03 04 05
Productivity (Quantity)
01 02 03 04 05

Electronic Nose

By genetically engineering the M13 bacteriophage to express specific amino acids on its surface, JENLiFE has developed an advanced electronic nose material that functions analogously to mammalian olfactory receptors.

Water Quality Monitoring

Seawater Monitoring Application

Soil Monitoring

Soil Monitoring Application

Odor Monitoring

Odor Monitoring Application

Human Breath Monitoring

Human Biofluid Monitoring

Biofoundry

Biofoundry Facilities

Establishing and operation of a semiconductor-grade biofoundry, along with biomaterial production facilities and genetic engineering laboratories

Large-scale fermentation of M13 phages

Large-capacity fermenters, large-capacity sterilizers and triple distilled water system

Library of over 8,000 M13 phages

M13 Phage Mass Cultivation

※ Phage CAPA: 273 mg/day

Constant Temperature and Humidity Facility

Temperature tolerance: ±1℃ to ±2℃ / Relative humidity tolerance: ±3% to ±5%

M13 Phage-based functional film

Fabrication of M13 Phage-based functional polymer film

※Film CAPA : 70 EA/day

Adopted Semiconductor-grade Automation Equipment

Temperature tolerance: ±1℃ to ±2℃ / Relative humidity tolerance: ±3% to ±5%

Laser dicing

Automated epoxy bonding

Device fabrication and commercialization technology

※ Sensor CAPA: 10 EA/hour

Research materials

Genetic engineering techniques for functional biomaterials

Techniques for fabricating 2D and 3D bio-derived structures compatible with semiconductor manufacturing processes

Smectic
Smectic
Chiral smectic C

Fabrication techniques for functional biofilms